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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.34
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ide) mitochondrion (Ide) extracellular space (Ide)
ATPase activity (Ide) nucleus (Ide)
Anatomy Link Frequency
pancreatic beta cells 2
brain 2
Ide (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 1 89.00 High High
imagery 31 53.68 Quite High
substance P 4 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 56 95.60 Very High Very High Very High
Diabetic Nephropathy 1 90.88 High High
Disease 28 89.88 High High
Fibrosis 1 89.00 High High
Cv Unclassified Under Development 1 86.16 High High
Congenital Anomalies 1 79.40 Quite High
Heart Disease 1 75.52 Quite High
Hypertension 2 74.12 Quite High
Coronary Artery Disease 2 73.56 Quite High
Coronary Heart Disease 8 70.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, if modification of hAChE by IDE occurs in vivo, both IDE and NEP deficiencies could alter the brain levels of CSR species and increase the risk of oligomerisation and fibril deposition.
Positive_regulation (increase) of Negative_regulation (deficiencies) of IDE in brain
1) Confidence 0.29 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1920558 Disease Relevance 0.06 Pain Relevance 0
Chemical induction of insulin deficiency by a cytotoxic agent for pancreatic beta cells, streptozotocin (STZ), produces a well-characterized model of type 1 diabetes [20].
Positive_regulation (induction) of Negative_regulation (deficiency) of insulin in pancreatic beta cells associated with diabetes mellitus
2) Confidence 0.07 Published 2007 Journal Cardiovasc Diabetol Section Body Doc Link PMC1805425 Disease Relevance 1.28 Pain Relevance 0.10

General Comments

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