INT204905

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.90
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr) signal transduction (Tlr4) plasma membrane (Tlr4)
intracellular (Tlr4) cytoplasm (Tlr4)
Anatomy Link Frequency
extracellular matrix 1
Tlr4 (Mus musculus)
gr (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 34 98.76 Very High Very High Very High
Central nervous system 15 87.84 High High
chemokine 3 74.32 Quite High
dexamethasone 4 62.36 Quite High
Demyelination 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Buprenorphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 37 98.76 Very High Very High Very High
Acute-phase Reaction 1 97.76 Very High Very High Very High
Infection 11 75.04 Quite High
Sepsis 1 71.60 Quite High
Meningeal Tuberculosis 1 64.40 Quite High
Mycobacterial Infection 1 60.08 Quite High
Death 7 50.00 Quite Low
Repression 4 35.60 Quite Low
Demyelinating Disease 6 5.00 Very Low Very Low Very Low
Meningitis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several genes that depend on GR to be induced by LPS play important roles in terms of cell differentiation, acute phase response, extracellular matrix organization and interferon response, all of which potentially helping to resolve inflammation rapidly.
LPS Positive_regulation (induced) of GR in extracellular matrix associated with acute-phase reaction and inflammation
1) Confidence 0.18 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1819560 Disease Relevance 0.90 Pain Relevance 0.38

General Comments

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