INT205056

Context Info Confidence 0.32 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.62 Pain Relevance 0

plasma membrane (LGALS4, COL17A1) cytosol (LGALS4) extracellular region (COL17A1) cell adhesion (LGALS4)

Anatomy Link Frequency leukocyte 2 LGALS4 (Homo sapiens) COL17A1 (Homo sapiens)

Pain Link Frequency Relevance Heat metalloproteinase 3 43.32 Chronic pancreatitis 1 5.00 Somatostatin 1 5.00

Disease Link Frequency Relevance Heat Adenocarcinoma 67 99.56 Cancer 41 74.56 Pancreatic Cancer 27 69.36 Leukemia 2 29.32 Islet Cell Adenoma 29 20.48 Sarcoma 2 18.64 Lymphatic System Cancer 5 18.28 Disease 10 5.00 Pancreatitis 9 5.00 Fibrosis 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

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Disease term

These genes include many not previously associated with pancreatic adenocarcinoma, such as galectin-4 (LGALS4), mucin 13 (MUC13), secretory leukocyte protease inhibitor (SLPI), collagen 17A1 (COL17A1), and ropporin 1-like (ROPN1L).

LGALS4 Negative_regulation (inhibitor) of Localization (secretory) of COL17A1 in leukocyte associated with adenocarcinoma

1) Confidence 0.32 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1824711 Disease Relevance 0.62 Pain Relevance 0

General Comments

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