INT205963

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (GLI1, SHH) embryo development (SHH) DNA binding (GLI1)
peptidase activity (SHH) extracellular space (SHH) cell death (SHH)
GLI1 (Homo sapiens)
SHH (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 1 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 3 100.00 Very High Very High Very High
Medulloblastoma 10 88.28 High High
Cancer 32 86.92 High High
Apoptosis 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Brain Tumor 2 5.00 Very Low Very Low Very Low
Metastasis 1 5.00 Very Low Very Low Very Low
Cerebral Palsy 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Disease Progression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gli1 activates Ptc1 expression and thus counters, to some extent Shh repression of Ptc1 activity [33,35,38].
Gli1 Positive_regulation (activates) of Negative_regulation (repression) of Shh associated with repression
1) Confidence 0.22 Published 2007 Journal BMC Syst Biol Section Body Doc Link PMC1839891 Disease Relevance 0.58 Pain Relevance 0

General Comments

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