INT206043

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.59
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Cd36) transport (Cd36) mitochondrion (Cd36)
cell adhesion (Cd36) Golgi apparatus (Cd36) plasma membrane (Cd36)
Anatomy Link Frequency
macrophage 1
monocytes 1
peritoneal macrophages 1
Cd36 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 133 86.80 High High
agonist 45 50.00 Quite Low
cytokine 56 5.00 Very Low Very Low Very Low
Arthritis 20 5.00 Very Low Very Low Very Low
Inflammatory response 18 5.00 Very Low Very Low Very Low
tolerance 9 5.00 Very Low Very Low Very Low
metalloproteinase 7 5.00 Very Low Very Low Very Low
ischemia 7 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
chemokine 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 96 99.28 Very High Very High Very High
Disorder Of Lipid Metabolism 45 98.72 Very High Very High Very High
Coronary Heart Disease 7 89.52 High High
Diabetes Mellitus 83 88.72 High High
Increased Venous Pressure Under Development 39 88.32 High High
INFLAMMATION 164 86.80 High High
Adhesions 21 85.12 High High
Hyperplasia 2 83.08 Quite High
Pathologic Processes 1 81.24 Quite High
Cancer 183 68.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both cholesterol efflux and the transcription of efflux-related receptors, namely CD36 and ATP-binding cassette protein A1, were increased by niacin.
Transcription (transcription) of CD36
1) Confidence 0.37 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2605342 Disease Relevance 0.69 Pain Relevance 0
ligands together have an additive effect on upregulation of CD36 production by potentiating the transcription of the CD36 gene in monocytes [226].
Transcription (transcription) of CD36 in monocytes
2) Confidence 0.21 Published 2010 Journal PPAR Research Section Body Doc Link PMC2829627 Disease Relevance 0.88 Pain Relevance 0.04
Incubation of IL-6 with MPM or IL-6 administration in mice increased macrophage Ox-LDL degradation and CD36 mRNA expression.
Transcription (expression) of CD36 in macrophage
3) Confidence 0.13 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.47 Pain Relevance 0
Ang II administration to apolipoprotein E-deficient atherosclerotic mice increases Ox-LDL degradation, CD36 mRNA expression, and CD36 protein expression by their peritoneal macrophages (MPMs).
Transcription (expression) of CD36 in peritoneal macrophages associated with atherosclerosis and disorder of lipid metabolism
4) Confidence 0.10 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.55 Pain Relevance 0

General Comments

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