INT206055

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.24
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F2, IL6) extracellular region (F2, IL6) peptidase activity (F2)
aging (IL6) plasma membrane (F2)
F2 (Homo sapiens)
IL6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 108 50.00 Quite Low
cytokine 54 5.00 Very Low Very Low Very Low
Arthritis 20 5.00 Very Low Very Low Very Low
Inflammatory response 16 5.00 Very Low Very Low Very Low
Inflammatory marker 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Atherosclerosis 88 99.92 Very High Very High Very High
Coagulation Disorder 4 75.36 Quite High
Thrombosis 2 71.84 Quite High
INFLAMMATION 136 50.00 Quite Low
Aging 42 50.00 Quite Low
Disorder Of Lipid Metabolism 12 15.52 Low Low
Dyslipidemia /

Combined Dyslipidemia

2 9.52 Low Low
Osteoporosis 70 5.00 Very Low Very Low Very Low
Diabetes Mellitus 66 5.00 Very Low Very Low Very Low
Cardiovascular Disease 40 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pharmacological inhibition of extracellular signal-regulated protein kinase (ERK), p38 mitogen-activated protein kinase (MAPK), or epidermal growth factor receptor (EGF-R) suppresses thrombin-induced IL-6 expression [87].
thrombin Positive_regulation (induced) of Gene_expression (expression) of IL-6
1) Confidence 0.01 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.61 Pain Relevance 0
Thrombin induces IL-6 mRNA and protein expression in a dose-dependent manner.
Thrombin Positive_regulation (induces) of Gene_expression (expression) of IL-6
2) Confidence 0.01 Published 2007 Journal Immun Ageing Section Body Doc Link PMC1845171 Disease Relevance 0.63 Pain Relevance 0

General Comments

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