INT206462

Context Info Confidence 0.39 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0.08

cytosol (SULT1B1) small molecule metabolic process (SULT1B1) cytoplasm (SULT1B1)

SULT1B1 (Homo sapiens)

Pain Link Frequency Relevance Heat Catecholamine 18 99.84 adenocard 4 56.96 Neurotransmitter 4 29.48 Dopamine 16 19.80 Inflammation 2 5.68 Paracetamol 2 5.00

Disease Link Frequency Relevance Heat Cancer 2 6.96 INFLAMMATION 2 5.68

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

For example, both SULT1C3 and SULT1B1 were stabilized by catecholamines in the absence of PAP, but neither showed significant activity toward this class of compounds.

Positive_regulation (stabilized) of SULT1B1 associated with catecholamine

1) Confidence 0.39 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1847840 Disease Relevance 0 Pain Relevance 0.08

The SULT1B1, SULT1C1, SULT1C2, SULT1C3, and SULT4A1 genes were amplified by PCR from the Mammalian Gene Collection clones and subcloned into a modified pET28a-LIC vector.

Positive_regulation (amplified) of SULT1B1

2) Confidence 0.39 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1847840 Disease Relevance 0 Pain Relevance 0

General Comments

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