INT206856

Context Info Confidence 0.04 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.76 Pain Relevance 0.10

endosome (Calcrl) aging (Adm) endoplasmic reticulum (Calcrl) signal transducer activity (Calcrl) response to stress (Adm) cytoplasm (Adm)

Adm (Rattus norvegicus) Calcrl (Rattus norvegicus)

Pain Link Frequency Relevance Heat calcitonin gene related peptide 2 99.60 Central nervous system 2 5.00 cytokine 2 5.00 agonist 2 5.00 fibrosis 2 5.00 Pain 2 5.00 alcohol 2 5.00

Disease Link Frequency Relevance Heat Apoptosis 18 95.96 Cancer 44 93.80 Uterine Fibroids 144 91.12 Rheumatoid Arthritis 46 5.00 Disease 10 5.00 Neuroblastoma 6 5.00 Endometriosis (extended) 4 5.00 Hyperplasia 2 5.00 Death 2 5.00 Chromosome Aberrations 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The calcitonin receptor-like receptor (CALCRL or CRLR), a G-protein coupled receptor, acts as a receptor for adrenomedullin (ADM) or calcitonin gene related peptide (CGRP) depending on which receptor activity modifying protein (RAMP) it partners with [47].

adrenomedullin Binding (receptor) of calcitonin receptor-like receptor associated with calcitonin gene related peptide

1) Confidence 0.04 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 0.88 Pain Relevance 0.05

The calcitonin receptor-like receptor (CALCRL or CRLR), a G-protein coupled receptor, acts as a receptor for adrenomedullin (ADM) or calcitonin gene related peptide (CGRP) depending on which receptor activity modifying protein (RAMP) it partners with [47].

adrenomedullin Binding (receptor) of CALCRL associated with calcitonin gene related peptide

2) Confidence 0.04 Published 2007 Journal BMC Womens Health Section Body Doc Link PMC1852551 Disease Relevance 0.87 Pain Relevance 0.05

General Comments

This test has worked.