INT207112

Context Info Confidence 0.68 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.24 Pain Relevance 0.12

cytoplasm (Sh2b2, Akt2) plasma membrane (Sh2b2, Akt2) transport (Akt2) mitochondrion (Akt2) carbohydrate metabolic process (Akt2) signal transducer activity (Sh2b2)

Sh2b2 (Mus musculus) Akt2 (Mus musculus)

Pain Link Frequency Relevance Heat dexamethasone 1 91.44 Inflammation 54 90.44 agonist 2 64.08 substance P 14 27.24 Inflammatory response 7 5.00 Inflammatory stimuli 5 5.00 cytokine 2 5.00 ketamine 2 5.00 Pain 1 5.00 c fibre 1 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 66 90.44 Cancer 9 79.44 Infection 1 14.16 Wound Healing 1 12.56 Injury 6 5.00 Cystitis 6 5.00 Disease 5 5.00 Overactive Bladder 3 5.00 Bladder Cancer 2 5.00 Death 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Others have shown that thrombin and PAR- APs induce Akt2 phosphorylation [69,70].

APs Positive_regulation (induce) of Phosphorylation (phosphorylation) of Akt2

1) Confidence 0.68 Published 2007 Journal BMC Physiol Section Body Doc Link PMC1853107 Disease Relevance 0.24 Pain Relevance 0.12

General Comments

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