INT207828

From wiki-pain
Revision as of 06:07, 21 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 0.14
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KCNJ5)
Anatomy Link Frequency
choroid plexus 1
KCNJ5 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 15 94.88 High High
antagonist 64 94.08 High High
Action potential 65 90.52 High High
gABA 41 80.32 Quite High
tetrodotoxin 80 59.48 Quite High
tolerance 16 47.84 Quite Low
Somatostatin 24 46.96 Quite Low
conotoxin 96 5.00 Very Low Very Low Very Low
addiction 26 5.00 Very Low Very Low Very Low
Glutamate 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 56 77.28 Quite High
Impaired Glucose Tolerance 16 49.20 Quite Low
Hyperinsulinism 8 32.80 Quite Low
Hypoglycemia 16 5.00 Very Low Very Low Very Low
Cystic Fibrosis 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Iizuka et al [68] reported Kir3.4 expression in the rat choroid plexus using both immunocytochemical and in situ hybridisation methods.
Gene_expression (expression) of Kir3.4 in choroid plexus
1) Confidence 0.58 Published 2007 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC2072944 Disease Relevance 0 Pain Relevance 0
cell in a dose-dependent manner through the membrane potential window supporting glucagon secretion in the depolarised (low KATP) to hyperpolarised (high KATP) direction (Figure 10C), the latter (in zero glucose) brings the ?
Gene_expression (direction) of KATP
2) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.09
Moderate re-activation of KATP channels with 2 ?
Gene_expression (channels) of KATP
3) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0
These were interpreted with the assumption that pharmacological KATP modulation only affects the ?
Gene_expression (modulation) of KATP
4) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.17
Half-maximal activation of KATP channels occurs at diazoxide concentrations of 20–100 ?
Gene_expression (channels) of KATP
5) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0.08 Pain Relevance 0
cell in a dose-dependent manner through the membrane potential window supporting glucagon secretion in the depolarised (low KATP) to hyperpolarised (high KATP) direction (Figure 10C), the latter (in zero glucose) brings the ?
Gene_expression (direction) of KATP
6) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.09
Increasing concentrations of the KATP channel activator diazoxide demonstrated that moderate activation of KATP channels (0.3–10 ?
Gene_expression (channels) of KATP
7) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.03
cell in a dose-dependent manner through the membrane potential window supporting glucagon secretion in the depolarised (low KATP) to hyperpolarised (high KATP) direction (Figure 10C), the latter (in zero glucose) brings the ?
Gene_expression (depolarised) of KATP
8) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0 Pain Relevance 0.09
cells express ATP-dependent K+ (KATP) channels [9,13,14,31,32] that can be closed by ATP [9,31].
Gene_expression (express) of KATP
9) Confidence 0.05 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1868042 Disease Relevance 0.06 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox