INT207836

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.19
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GAD2) lyase activity (GAD2) Golgi apparatus (GAD2)
cytoplasmic membrane-bounded vesicle (GAD2) plasma membrane (GAD2) cytoplasm (GAD2)
Anatomy Link Frequency
blood 1
GAD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Cannabinoid receptor 14 97.76 Very High Very High Very High
Action potential 8 91.88 High High
GABAergic 69 82.44 Quite High
gABA 41 74.76 Quite High
conotoxin 12 74.40 Quite High
tetrodotoxin 10 5.00 Very Low Very Low Very Low
antagonist 8 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
Somatostatin 3 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 7 97.44 Very High Very High Very High
Lifespan 27 97.12 Very High Very High Very High
Aging 17 48.72 Quite Low
Amblyopia 7 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 2 5.00 Very Low Very Low Very Low
Hypoglycemia 2 5.00 Very Low Very Low Very Low
Cataract 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low
Hyperinsulinism 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
2), a biphasic increase then decrease (GAD65, Gephyrin), or multiple increases and decreases (VGAT, CB1) across the lifespan.
Negative_regulation (decrease) of GAD65 associated with cannabinoid receptor and lifespan
1) Confidence 0.37 Published 2010 Journal Frontiers in Cellular Neuroscience Section Body Doc Link PMC2893712 Disease Relevance 0.10 Pain Relevance 0.37
cells of the pancreatic islets of Langerhans is suppressed by elevated blood sugar, a response that is often perturbed in diabetes.
Negative_regulation (suppressed) of islets in blood associated with diabetes mellitus
2) Confidence 0.01 Published 2007 Journal PLoS Biology Section Abstract Doc Link PMC1868042 Disease Relevance 0.10 Pain Relevance 0.08

General Comments

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