INT208332

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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.30
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

enzyme regulator activity (Apoc3) lipid binding (Apoc3) transport (Apoc3)
extracellular space (Apoc3) extracellular region (Apoc3)
Anatomy Link Frequency
body 1
Apoc3 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 3 85.16 High High
alcohol 6 58.88 Quite High
psoriasis 126 50.00 Quite Low
Central nervous system 8 20.04 Low Low
Inflammation 32 5.00 Very Low Very Low Very Low
drug abuse 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperlipidemia 14 99.24 Very High Very High Very High
Body Weight 71 98.44 Very High Very High Very High
Psoriasis 212 97.88 Very High Very High Very High
Disorder Of Lipid Metabolism 167 97.48 Very High Very High Very High
Obesity 145 86.00 High High
Nicotine Addiction 4 79.80 Quite High
Syndrome 4 76.68 Quite High
Atherosclerosis 22 68.04 Quite High
Cardiovascular Disease 32 61.52 Quite High
Infection 2 38.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In most studies, elevated levels of apoA1, apoB [16, 43], apoC3, and apoE [41, 76–78] were detected in the serum of psoriatic patients compared to the healthy control group.
Positive_regulation (elevated) of apoC3 associated with psoriasis
1) Confidence 0.29 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2914266 Disease Relevance 1.09 Pain Relevance 0.03
It is known that an increase in apoC3 levels induces the development of hypertriglyceridemia.
Positive_regulation (increase) of apoC3 associated with hyperlipidemia
2) Confidence 0.29 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2914266 Disease Relevance 1.01 Pain Relevance 0.03
Moreover, these changes in ACOX and apo C-III mRNA did not correlate with increased body weight and adiposity.
Positive_regulation (changes) of C-III in body associated with body weight
3) Confidence 0.04 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943125 Disease Relevance 0.84 Pain Relevance 0
-mercaptoethanol significantly increased the number of apoE3 molecules associated with EM (Fig. 6), indicating that when apoE3 remains as a monomer, more apoE3 monomers can associate with EM than apoE3 dimers.
Positive_regulation (increased) of apoE3
4) Confidence 0.02 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 0.35 Pain Relevance 0.04

General Comments

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