INT208341

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.83
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 4
Hdl1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 24 67.00 Quite High
addiction 9 38.72 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 279 100.00 Very High Very High Very High
Disease 15 5.00 Very Low Very Low Very Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
g/ml, respectively (Table 1), the apoE-isoform-specific cholesterol release was observed (Fig. 4) as was the case for apoE-HDL (Fig. 1), that is, apoE3-EM and apoE3-HDL induced cholesterol release from neurons, whereas apoE4-EM and apoE4-HDL induced little release.
Positive_regulation (induced) of Localization (release) of HDL in neurons associated with disorder of lipid metabolism
1) Confidence 0.10 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 0.30 Pain Relevance 0
Moreover, as we previously reported [10], apoE4-HDL contains number of apoE molecules per particle twofold that of apoE3; however, apoE4-HDL induced a very-weak cholesterol release, whereas apoE3-HDL induced a strong cholesterol release (Figs. 1A and 1B).
Positive_regulation (induced) of Localization (release) of HDL associated with disorder of lipid metabolism
2) Confidence 0.10 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 1.23 Pain Relevance 0.03
g/ml, respectively (Table 1), the apoE-isoform-specific cholesterol release was observed (Fig. 4) as was the case for apoE-HDL (Fig. 1), that is, apoE3-EM and apoE3-HDL induced cholesterol release from neurons, whereas apoE4-EM and apoE4-HDL induced little release.
Positive_regulation (induced) of Localization (release) of HDL in neurons associated with disorder of lipid metabolism
3) Confidence 0.10 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 0.30 Pain Relevance 0

General Comments

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