INT209250

Context Info Confidence 0.06 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.82 Pain Relevance 0.68

cytosol (TRPV1) transport (TRPV1) nucleus (DRGX) plasma membrane (TRPV1) lipid metabolic process (TRPV1)

Anatomy Link Frequency dorsal root ganglion 2 TRPV1 (Homo sapiens) DRGX (Homo sapiens)

Pain Link Frequency Relevance Heat dorsal root ganglion 32 100.00 Thermal hyperalgesia 1 90.08 qutenza 6 85.64 Pain 17 70.68 Eae 1 68.08 Neuropeptide 1 55.60 substance P 1 54.48 sodium channel 3 47.84 Spinal cord 11 5.00 diabetic neuropathy 8 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 33 100.00 Injury 20 98.64 Hyperalgesia 3 90.08 Nervous System Injury 9 85.28 Pain 10 70.68 Neuropathic Pain 15 68.08 Nociception 3 51.60 Hypersensitivity 3 36.96 Neuroma 4 18.96 Diabetes Mellitus 25 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition to its co-localization with TRPV1 in small/medium diameter sensory neurons of the dorsal root ganglion (DRG), the number of both TRPV3- and TRPV1- immunoreactive sensory neurons increased significantly after DRG avulsion injury i.e. central axotomy [4].

TRPV1 Positive_regulation (increased) of Localization (localization) of DRG in dorsal root ganglion associated with ganglion cysts, dorsal root ganglion and injury

1) Confidence 0.06 Published 2007 Journal BMC Neurol Section Body Doc Link PMC1892784 Disease Relevance 0.82 Pain Relevance 0.68

General Comments

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