INT209366

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.92
Pain Relevance 1.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (GSX1)
Anatomy Link Frequency
plasma 1
liver 1
GSX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 192 97.60 Very High Very High Very High
alcohol 56 87.84 High High
Analgesic 12 74.28 Quite High
abdominal pain 6 54.24 Quite High
Pain 6 38.48 Quite Low
cINOD 12 5.00 Very Low Very Low Very Low
aspirin 6 5.00 Very Low Very Low Very Low
withdrawal 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 32 97.40 Very High Very High Very High
Alcohol Addiction 8 87.12 High High
Appetite Loss 8 83.28 Quite High
Hepatotoxicity 4 68.64 Quite High
Abdominal Pain 6 54.24 Quite High
Ataxia 2 46.76 Quite Low
Confusion 2 45.44 Quite Low
Death 2 43.36 Quite Low
Liver Failure 4 42.96 Quite Low
Infection 2 39.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If GSH stores are depleted, NAPQI can bind to hepatocellular components resulting in liver injury.
Negative_regulation (depleted) of GSH in liver associated with injury
1) Confidence 0.42 Published 2007 Journal BMC Med Section Body Doc Link PMC1894983 Disease Relevance 0.55 Pain Relevance 0.76
Published data suggest that that the plasma GSH concentration is decreased in alcoholic subjects [4], particularly in those ingesting acetaminophen [5].
Negative_regulation (decreased) of GSH in plasma associated with paracetamol
2) Confidence 0.42 Published 2007 Journal BMC Med Section Body Doc Link PMC1894983 Disease Relevance 0.36 Pain Relevance 0.96

General Comments

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