INT209879

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (CSF2, TNFRSF11B) signal transduction (TNFRSF11B) extracellular space (CSF2)
proteinaceous extracellular matrix (TNFRSF11B) extracellular matrix organization (TNFRSF11B)
Anatomy Link Frequency
neutrophils 2
CSF2 (Homo sapiens)
TNFRSF11B (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 12 98.68 Very High Very High Very High
rheumatoid arthritis 58 98.16 Very High Very High Very High
Inflammation 31 75.96 Quite High
antagonist 1 64.16 Quite High
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 58 98.16 Very High Very High Very High
Apoptosis 8 84.88 Quite High
Cancer 9 80.08 Quite High
Necrosis 9 79.60 Quite High
INFLAMMATION 30 75.96 Quite High
Hypercalcemia 2 73.40 Quite High
Immune System Diseases 1 46.24 Quite Low
Disease Progression 1 29.08 Quite Low
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, and GM-CSF cannot induce neutrophils to express the high concentrations of OPG observed with neutrophils from patients with RA, other factors are involved in inducing OPG.
GM-CSF Positive_regulation (induce) of Gene_expression (express) of OPG in neutrophils associated with rheumatoid arthritis
1) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906801 Disease Relevance 0.76 Pain Relevance 0.26

General Comments

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