INT210549

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (BCHE, Ache) extracellular region (BCHE, Ache) nuclear envelope (Ache)
Golgi apparatus (Ache) endoplasmic reticulum (BCHE) enzyme binding (BCHE)
Anatomy Link Frequency
brain 1
BCHE (Homo sapiens)
Ache (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 1 78.68 Quite High
substance P 4 78.08 Quite High
Central nervous system 2 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Amyloid Plaque 4 99.76 Very High Very High Very High
Disease 27 94.68 High High
Cognitive Disorder 2 81.04 Quite High
Death 2 71.84 Quite High
Alzheimer's Dementia 38 58.24 Quite High
Targeted Disruption 2 39.52 Quite Low
Neurodegenerative Disease 6 25.36 Quite Low
Creutzfeldt Jakob Disease 1 5.08 Very Low Very Low Very Low
Aids-related Complex 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The evidence is as follows; both human acetylcholinesterase (hAChE) and butyrylcholinesterase (hBuChE) are associated with senile plaques and both the pattern of hAChE oligomerisation and its enzymatic activity are altered in brain areas affected by AD [12], [13], [16], [14], [17].
butyrylcholinesterase Binding (associated) of acetylcholinesterase in brain associated with disease and amyloid plaque
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1920558 Disease Relevance 0.82 Pain Relevance 0.12

General Comments

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