INT210663

Context Info Confidence 0.05 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.10 Pain Relevance 0

cell proliferation (Txnrd1) cytosol (Txnrd1) mitochondrion (Txnrd1) oxidoreductase activity (Txnrd1) nucleolus (Txnrd1) nucleus (Txnrd1)

Txnrd1 (Mus musculus)

Pain Link Frequency Relevance Heat withdrawal 5 5.00 ischemia 1 5.00 qutenza 1 5.00

Disease Link Frequency Relevance Heat Stress 9 95.36 Disease 8 5.00 Toxicity 2 5.00 Parkinson's Disease 1 5.00 Hypoxia 1 5.00 Coronary Artery Disease 1 5.00 Apoptosis 1 5.00 Drug Induced Neurotoxicity 1 5.00 Aging 1 5.00 Neurodegenerative Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Complex I blockade upregulated the mRNA levels of glutamylcysteine synthetase heavy and light chains, glutathione-S-transferases omega1 and alpha 2, hemoxygenase 1, thioredoxin reductase 1, and selenoprotein H.

Positive_regulation (upregulated) of thioredoxin reductase 1

1) Confidence 0.05 Published 2007 Journal International Journal of Biological Sciences Section Abstract Doc Link PMC1925139 Disease Relevance 0.10 Pain Relevance 0

General Comments

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