INT210795

Context Info Confidence 0.30 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0.17

plasma membrane (Ihh, Itgb1) cell differentiation (Ihh) peptidase activity (Ihh) extracellular region (Ihh) cell adhesion (Itgb1) embryo development (Ihh)

Ihh (Mus musculus) Itgb1 (Mus musculus)

Pain Link Frequency Relevance Heat metalloproteinase 4 100.00 dexamethasone 188 67.36 cytokine 18 5.00 Inflammation 8 5.00 chemokine 4 5.00 cINOD 2 5.00 alcohol 2 5.00 agonist 2 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 10 5.00 Hypertrophy 8 5.00 Apoptosis 6 5.00 Osteoporosis 6 5.00 Cancer 6 5.00 Targeted Disruption 4 5.00 Necrosis 4 5.00 Leukemia 4 5.00 Natriuresis 2 5.00 Repression 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Probes for Indian hedgehog (Ihh), Tissue inhibitor of matrix metalloproteinase 4 (Timp4), Cyclin-dependent kinase inhibitor 1C (Cdkn1c, p57), Integrin beta like 1 protein (Itgbl1), GC receptor (Nr3c1), Integrin beta 1 (Itgb1) and Kruppel-like factor 15 (Klf15) were assayed using the TaqMan® gene expression assays in accordance with the manufacturers directions.

Ihh Negative_regulation (inhibitor) of Itgb1 associated with metalloproteinase

1) Confidence 0.30 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1929075 Disease Relevance 0 Pain Relevance 0.08

Probes for Indian hedgehog (Ihh), Tissue inhibitor of matrix metalloproteinase 4 (Timp4), Cyclin-dependent kinase inhibitor 1C (Cdkn1c, p57), Integrin beta like 1 protein (Itgbl1), GC receptor (Nr3c1), Integrin beta 1 (Itgb1) and Kruppel-like factor 15 (Klf15) were assayed using the TaqMan® gene expression assays in accordance with the manufacturers directions.

Ihh Negative_regulation (inhibitor) of Integrin beta 1 associated with metalloproteinase

2) Confidence 0.30 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1929075 Disease Relevance 0 Pain Relevance 0.08

General Comments

This test has worked.