INT211746

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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) plasma membrane (Oprm1) signal transducer activity (Oprm1)
Anatomy Link Frequency
neurons 1
ganglia 1
Oprm1 (Mus musculus)
Mors1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 216 100.00 Very High Very High Very High
Nucleus accumbens 2 100.00 Very High Very High Very High
Morphine 182 99.14 Very High Very High Very High
Spinal cord 6 93.72 High High
Immobilon 4 89.04 High High
MU agonist 8 88.32 High High
tolerance 86 76.32 Quite High
Opioid 84 75.92 Quite High
agonist 42 49.12 Quite Low
Intracerebroventricular 4 42.72 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 24 5.00 Very Low Very Low Very Low
Drug Dependence 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Inflammatory Pain 4 5.00 Very Low Very Low Very Low
Decapitation 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Notably, and in contrast to what is observed in cultured cells, morphine produces some membrane trafficking of the MORs in dendrites of nucleus accumbens neurons and more extensive MOR internalization in embryonic striatal neurons and ganglia neurons [17-19].
MOR Binding (internalization) of MORs in neurons associated with nucleus accumbens, opioid receptor and morphine
1) Confidence 0.08 Published 2007 Journal Mol Pain Section Body Doc Link PMC1947952 Disease Relevance 0 Pain Relevance 0.89
Notably, and in contrast to what is observed in cultured cells, morphine produces some membrane trafficking of the MORs in dendrites of nucleus accumbens neurons and more extensive MOR internalization in embryonic striatal neurons and ganglia neurons [17-19].
MOR Binding (internalization) of MORs in ganglia associated with nucleus accumbens, opioid receptor and morphine
2) Confidence 0.03 Published 2007 Journal Mol Pain Section Body Doc Link PMC1947952 Disease Relevance 0 Pain Relevance 0.89

General Comments

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