INT213243

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Latest revision as of 03:14, 21 September 2012

Context Info
Confidence 0.42
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 2.68
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (DBP)
Anatomy Link Frequency
epithelium 2
DBP (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 12 96.32 Very High Very High Very High
antagonist 11 50.00 Quite Low
Inflammation 22 43.92 Quite Low
ischemia 2 41.56 Quite Low
Inflammatory response 2 31.24 Quite Low
Bioavailability 1 28.08 Quite Low
Central nervous system 11 26.76 Quite Low
Inflammatory marker 2 15.08 Low Low
beta blocker 18 5.00 Very Low Very Low Very Low
cva 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 10 100.00 Very High Very High Very High
Neuromyelitis Optica 162 99.68 Very High Very High Very High
Hypertension 225 97.74 Very High Very High Very High
Diabetes Mellitus 140 97.40 Very High Very High Very High
Demyelinating Disease 18 96.32 Very High Very High Very High
Clinical Trials And Case Reports 4 72.64 Quite High
Stroke 69 67.60 Quite High
Motor Neuron Diseases 2 60.48 Quite High
Increased Venous Pressure Under Development 16 59.36 Quite High
Injury 6 58.96 Quite High

[edit] Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, with the valsartan/amlodipine combination, the further mean reduction in BP (SBP/DBP: ?
Negative_regulation (reduction) of Gene_expression (/) of DBP
1) Confidence 0.42 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2835558 Disease Relevance 0 Pain Relevance 0
The mean maximum decrease in DBP was ?
Negative_regulation (decrease) of Gene_expression (was) of DBP
2) Confidence 0.22 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717814 Disease Relevance 0.09 Pain Relevance 0
In our current study, 2-DE and western blot analysis revealed significantly reduced levels of DBP in the CSF samples from the NMO group.
Negative_regulation (reduced) of Gene_expression (levels) of DBP associated with neuromyelitis optica
3) Confidence 0.16 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2730746 Disease Relevance 0.81 Pain Relevance 0.20
-glycoprotein (A1BG), DBP, fibrinogen gamma chain (FGG), pigment epithelium-derived factor (PEDF), apolipoprotein A-IV (ApoA-IV), apolipoprotein E (ApoE), and transthyretin (TTR) were downregulated in the NMO group in comparison to the control group.
Negative_regulation (downregulated) of Gene_expression (chain) of DBP in epithelium associated with neuromyelitis optica and disorder of lipid metabolism
4) Confidence 0.16 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2730746 Disease Relevance 0.59 Pain Relevance 0
3.72 mmHg, P=0.03 for z score for overall effect; DBP ?
Negative_regulation (effect) of Gene_expression (overall) of DBP
5) Confidence 0.16 Published 2007 Journal Core Evidence Section Body Doc Link PMC3012553 Disease Relevance 0.40 Pain Relevance 0
A total of 76% of patients administered the 30/12.5 mg combination exhibited normalized BP or a DBP reduction ?
Negative_regulation (exhibited) of Gene_expression (reduction) of DBP
6) Confidence 0.12 Published 2006 Journal Vascular Health and Risk Management Section Body Doc Link PMC1994025 Disease Relevance 0.06 Pain Relevance 0
A subsequent small crossover trial in 38 patients with type 2 diabetes and hypertension,119 assigned to benazepril 10 mg/day, amlodipine 5 mg/day or their combination, showed that combination therapy produced a significantly greater reduction in both SBP and DBP than either drug alone, with a mean decrease in BP of ?
Negative_regulation (reduction) of Gene_expression (produced) of DBP associated with diabetes mellitus and hypertension
7) Confidence 0.10 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2686259 Disease Relevance 0.73 Pain Relevance 0

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