INT213359

Context Info Confidence 0.05 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.62 Pain Relevance 0.04

nucleus (Spdef) DNA binding (Spdef)

Spdef (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 7 75.96 agonist 2 5.56 palliative 2 5.00

Disease Link Frequency Relevance Heat Cancer 99 85.68 Prostate Cancer 19 71.68 Apoptosis 14 54.84 Fibrosis 2 5.00 Carcinoma 2 5.00 Necrosis 1 5.00 Severe Combined Immunodeficiency 1 5.00 Infection 1 5.00 Fibrosarcoma 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Transfection of AR-siRNA in LNCaP cells strongly inhibits the androgen-induced transcription of Prostate Specific Antigen (PSA), a prototypic AR-target gene (Figure 1B).

Positive_regulation (induced) of Transcription (transcription) of Prostate Specific Antigen

1) Confidence 0.05 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1994591 Disease Relevance 0.62 Pain Relevance 0.04

General Comments

This test has worked.