INT213360

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Context Info
Confidence 0.06
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.44
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Spdef) DNA binding (Spdef)
Spdef (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 14 90.80 High High
agonist 4 5.24 Low Low
palliative 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 198 95.44 Very High Very High Very High
Prostate Cancer 38 71.36 Quite High
Necrosis 2 67.04 Quite High
Apoptosis 28 63.84 Quite High
Fibrosarcoma 2 14.48 Low Low
Fibrosis 4 5.00 Very Low Very Low Very Low
Carcinoma 4 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At that time, the Prostate Specific Antigen (PSA) mRNA was strongly repressed in the hAR-siRNA and in the bicalutamide groups, while AR mRNA level was repressed only in the hAR-siRNA treated tumors (Figure 1F).


Transcription (repressed) of Prostate Specific Antigen associated with cancer
1) Confidence 0.06 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1994591 Disease Relevance 0.82 Pain Relevance 0.05
Transfection of AR-siRNA in LNCaP cells strongly inhibits the androgen-induced transcription of Prostate Specific Antigen (PSA), a prototypic AR-target gene (Figure 1B).
Transcription (transcription) of Prostate Specific Antigen
2) Confidence 0.06 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1994591 Disease Relevance 0.62 Pain Relevance 0.04

General Comments

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