INT214149

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Context Info
Confidence 0.33
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lepr, Pomc) extracellular space (Lepr, Pomc) extracellular region (Lepr, Pomc)
generation of precursor metabolites and energy (Pomc) plasma membrane (Lepr) cell-cell signaling (Pomc)
Anatomy Link Frequency
hypothalamus 1
Lepr (Mus musculus)
Pomc (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 3 56.88 Quite High
Kinase C 1 26.68 Quite Low
Action potential 4 6.72 Low Low
medulla 27 5.00 Very Low Very Low Very Low
Central nervous system 15 5.00 Very Low Very Low Very Low
antagonist 10 5.00 Very Low Very Low Very Low
agonist 10 5.00 Very Low Very Low Very Low
Cholecystokinin 8 5.00 Very Low Very Low Very Low
amygdala 8 5.00 Very Low Very Low Very Low
gABA 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Thinness 2 88.56 High High
Weight Gain 4 65.52 Quite High
Eating Disorder 1 59.56 Quite High
Obesity 57 37.84 Quite Low
Anorexia 14 5.00 Very Low Very Low Very Low
Appetite Loss 10 5.00 Very Low Very Low Very Low
Sprains And Strains 5 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both the POMC/CART and NPY/AgRP pathways express LEPRB and project to the leptin-dependent regions in the DMH, PVN and lateral hypothalamus (Table 1).
leptin-dependent Binding (project) of POMC in hypothalamus
1) Confidence 0.33 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.21 Pain Relevance 0.03

General Comments

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