INT214705

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Context Info
Confidence 0.57
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.15
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

kinase activity (Tk1) cytoplasm (Tk1)
Anatomy Link Frequency
TK-1 1
B16-F10 1
Tk1 (Mus musculus)
Pain Link Frequency Relevance Heat
positron emission tomography 50 99.02 Very High Very High Very High
imagery 48 91.60 High High
Inflammation 4 56.68 Quite High
isoflurane 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 36 100.00 Very High Very High Very High
Cancer 174 99.52 Very High Very High Very High
Skin Cancer 35 98.20 Very High Very High Very High
Infection 13 77.72 Quite High
Malignant Neoplastic Disease 4 60.60 Quite High
Recurrence 1 57.12 Quite High
INFLAMMATION 4 56.68 Quite High
Herpes Simplex Virus 4 50.00 Quite Low
Squamous Cell Neoplasms 1 50.00 Quite Low
Hypoxia 1 48.64 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HSV1-tk–expressing bacteria have recently been shown to localize in various tumors, including B16-F10 murine melanoma cells, and primary tumors were successfully imaged with [124I]FIAU or [18F]FEAU [41], [42].
Localization (localize) of HSV1-tk in B16-F10 associated with cold sores, cancer and skin cancer
1) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2651472 Disease Relevance 1.67 Pain Relevance 0.09
Therefore, the time between irradiation and PET scan should be as long as possible to allow for recovery of TK-1 from short-term irradiation effects.
Localization (recovery) of TK-1 in TK-1 associated with positron emission tomography
2) Confidence 0.47 Published 2007 Journal Mol Imaging Biol Section Body Doc Link PMC2040178 Disease Relevance 0.48 Pain Relevance 0.12

General Comments

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