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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 1.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos) response to stress (Fos)
Anatomy Link Frequency
brush 2
Ap3d1 (Rattus norvegicus)
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 18 98.78 Very High Very High Very High
Pain 20 91.96 High High
Dorsal horn neuron 5 84.88 Quite High
Dorsal horn 54 81.80 Quite High
central sensitization 2 81.04 Quite High
intrathecal 1 75.04 Quite High
allodynia 31 66.64 Quite High
Brush evoked pain 10 63.52 Quite High
Neuropathic pain 8 61.12 Quite High
IPN 1 54.80 Quite High
Disease Link Frequency Relevance Heat
Pain 21 91.96 High High
Neuropathic Pain 51 66.64 Quite High
Inflammatory Pain 1 54.80 Quite High
INFLAMMATION 1 36.32 Quite Low
Nociception 38 32.80 Quite Low
Hyperalgesia 1 23.40 Low Low
Stroke 5 5.00 Very Low Very Low Very Low
Syndrome 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 3 5.00 Very Low Very Low Very Low
Nervous System Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since lamina I neurons seem to lack functional NMDA receptors [82] (but see references [83], [84] for divergent data) and d-AP5 blocked Fos expression not only in lamina I neurons, but also in lamina II-III interneurons, we would like to suggest that brush-activation of PKC?
d-AP5 Negative_regulation (blocked) of Gene_expression (expression) of Fos in brush associated with nmda receptor
1) Confidence 0.00 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2043493 Disease Relevance 0.39 Pain Relevance 1.04

General Comments

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