INT215345

Context Info Confidence 0.05 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.16 Pain Relevance 0

DNA binding (Srebf1, Tbp) cytoplasm (Srebf1, Tbp) nucleus (Srebf1, Tbp) Golgi apparatus (Srebf1) endoplasmic reticulum (Srebf1) protein complex (Srebf1)

Anatomy Link Frequency upper 2 Srebf1 (Mus musculus) Tbp (Mus musculus)

Pain Link Frequency Relevance Heat addiction 3 5.00 fluoxetine 2 5.00

Disease Link Frequency Relevance Heat Disease 5 92.64 Stress 1 71.12 Death 11 7.76 Apoptosis 15 5.00 Neurodegenerative Disease 5 5.00 Neuroblastoma 1 5.00 Targeted Disruption 1 5.00 Dementia 1 5.00 Spinocerebellar Ataxia Type 2 1 5.00 Tremor 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

On the other hand, TBP occupancy at the sterol repressor element 1 (SRE1) site, further upstream was enhanced in the presence of expanded polyQ variants (Fig. 4C, upper).

Positive_regulation (enhanced) of sterol repressor element 1 Binding (occupancy) of TBP in upper

1) Confidence 0.05 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2064964 Disease Relevance 0.16 Pain Relevance 0

General Comments

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