INT215683

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (P2ry2, Il6) mitochondrion (P2ry2) embryo development (P2ry2)
signal transducer activity (P2ry2) extracellular space (Il6) extracellular region (Il6)
Anatomy Link Frequency
microglial cells 2
P2ry2 (Rattus norvegicus)
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 4 98.72 Very High Very High Very High
cytokine 3 61.76 Quite High
antagonist 18 58.64 Quite High
Central nervous system 13 58.60 Quite High
adenocard 12 53.92 Quite High
Neurotransmitter 12 43.92 Quite Low
Hippocampus 13 42.72 Quite Low
Glutamate 9 40.48 Quite Low
gABA 4 39.48 Quite Low
ischemia 9 33.20 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 5 98.72 Very High Very High Very High
Stress 2 93.24 High High
Apoptosis 4 79.36 Quite High
Neurological Disease 1 76.88 Quite High
Epilepsy 4 75.04 Quite High
Hypoxia 7 48.92 Quite Low
Cv Unclassified Under Development 8 33.20 Quite Low
Convulsion 3 25.12 Quite Low
Muscle Weakness 1 18.48 Low Low
Brain Injury 1 16.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
P2Y rather than P2X7 receptors seem to have a major role in the IL-6 production by microglial cells [135].
P2Y Positive_regulation (role) of Gene_expression (production) of IL-6 in microglial cells
1) Confidence 0.02 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072925 Disease Relevance 0.76 Pain Relevance 0.29

General Comments

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