INT215942

Context Info Confidence 0.03 First Reported 2007 Last Reported 2007 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.95 Pain Relevance 0.20

peptidase activity (Mmp14) cytoplasm (Mmp14)

Mmp14 (Mus musculus) Eae1 (Mus musculus)

Pain Link Frequency Relevance Heat metalloproteinase 65 87.20 Central nervous system 30 79.36 Spinal cord 9 74.44 cytokine 10 5.00 Inflammation 6 5.00 chemokine 6 5.00 Multiple sclerosis 3 5.00 anesthesia 1 5.00 glial activation 1 5.00 Inflammatory mediators 1 5.00

Disease Link Frequency Relevance Heat Multiple Sclerosis 51 100.00 Sprains And Strains 2 99.60 Disease 6 97.72 Targeted Disruption 17 19.20 Injury 10 5.00 INFLAMMATION 7 5.00 Cancer 5 5.00 Bordatella Infection 3 5.00 Paralysis 3 5.00 Mycobacterial Infection 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Taken together, this shows that the pattern of MT-MMP regulation in severe EAE is independent of mouse strain, myelin antigen, and use of adjuvant in disease induction.

Neg (independent) Regulation (independent) of MT-MMP Regulation (regulation) of EAE associated with multiple sclerosis, disease and sprains and strains

1) Confidence 0.03 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2075488 Disease Relevance 0.95 Pain Relevance 0.20

General Comments

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