INT216914

Context Info Confidence 0.23 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.01 Pain Relevance 0.46

plasma membrane (P2rx5)

P2rx5 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Neuropathic pain 34 82.60 inferior alveolar nerve 1 80.32 Sciatic nerve 3 78.72 Dorsal horn 12 65.44 Peripheral nerve injury 6 55.24 Inflammation 9 45.92 Stimulus evoked pain 5 45.36 bradykinin 1 26.60 substance P 1 23.24 allodynia 17 23.20

Disease Link Frequency Relevance Heat Nervous System Injury 38 99.20 Injury 5 89.72 Neuropathic Pain 72 82.60 Hypersensitivity 8 57.04 INFLAMMATION 10 45.92 Hyperalgesia 7 22.08 Pain 35 5.00 Inflammatory Pain 10 5.00 Infection 3 5.00 Diabetes Mellitus 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Messenger RNAs of P2X5 and P2X6 are increased and decreased, respectively, in the injured DRG [124].

Positive_regulation (increased) of P2X5

1) Confidence 0.23 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096756 Disease Relevance 1.01 Pain Relevance 0.46

General Comments

This test has worked.