INT217167

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.43
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
pancreas 2
THP-1 2
synovium 2
MIR155 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 125 99.84 Very High Very High Very High
Osteoarthritis 25 98.88 Very High Very High Very High
beta blocker 1 86.08 High High
Inflammation 25 85.12 High High
psoriasis 2 80.04 Quite High
cytokine 18 31.40 Quite Low
Arthritis 1 11.56 Low Low
ischemia 8 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 125 99.84 Very High Very High Very High
Pancreatic Cancer 7 99.16 Very High Very High Very High
Osteoarthritis 24 98.88 Very High Very High Very High
Colon Cancer 9 98.28 Very High Very High Very High
Acute Monocytic Leukemia 1 96.32 Very High Very High Very High
Chronic Lymphoid Leukemia 8 95.68 Very High Very High Very High
Myocardial Infarction 4 88.08 High High
INFLAMMATION 27 85.12 High High
Cancer 61 84.72 Quite High
Coronary Artery Disease 4 84.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Besides, Roldo et al. showed that the expression of miR-103 and miR-107, associating with a lack of miR-155 expression, could discriminate pancreatic tumors from normal pancreas.
Negative_regulation (lack) of Gene_expression (expression) of miR-155 in pancreas associated with pancreatic cancer
1) Confidence 0.23 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 0.76 Pain Relevance 0
The abnormal expression of miR-146 and miR-155 is also found in the synovium of RA patients, while the expression of these miRNAs is markedly upregulated in SF after stimulation with TNF-?
Negative_regulation (abnormal) of Gene_expression (expression) of miR-155 in synovium associated with rheumatoid arthritis
2) Confidence 0.09 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911863 Disease Relevance 0.90 Pain Relevance 0.32
The expression level of miR-26a, miR-146a/b, miR-150 and miR-155 in RA patients were significantly higher than in healthy subjects.
Negative_regulation (level) of Gene_expression (expression) of miR-155 associated with rheumatoid arthritis
3) Confidence 0.07 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2950393 Disease Relevance 1.10 Pain Relevance 0.55
Resveratrol decreases the levels of miR-155 in THP-1 and modulating JunB and JunD, key regulators in carcinogenesis [31].
Negative_regulation (decreases) of Gene_expression (levels) of miR-155 in THP-1
4) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3009730 Disease Relevance 0.66 Pain Relevance 0.04

General Comments

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