INT21871

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Context Info
Confidence 0.14
First Reported 1990
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.78
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lipg) extracellular space (Lipg) extracellular region (Lipg)
molecular_function (Lipg)
Anatomy Link Frequency
plasma 1
endothelium 1
Lipg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 5 92.48 High High
withdrawal 1 92.04 High High
tolerance 1 89.08 High High
Pain 3 85.44 High High
headache 3 41.28 Quite Low
abdominal pain 1 25.00 Low Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
bDMF 5 5.00 Very Low Very Low Very Low
hyperexcitability 4 5.00 Very Low Very Low Very Low
Dopamine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 1 93.72 High High
Cv General 3 Under Development 5 92.48 High High
Disease 1 90.96 High High
Pain 1 85.44 High High
Pressure And Volume Under Development 2 85.20 High High
Hypertension 1 71.08 Quite High
Urological Neuroanatomy 8 50.00 Quite Low
Headache 3 41.28 Quite Low
Pancreatitis 1 25.68 Quite Low
Abdominal Pain 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transcripts with a significant compound by EDL interaction were further analyzed using a one-way ANOVA with dose as the independent variable followed by Dunnett's mean contrast test.
EDL Binding (interaction) of
1) Confidence 0.14 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2626604 Disease Relevance 0 Pain Relevance 0
The hyperaemic response that follows the liberation of endothelial-derived relaxing factor (EDRF) by sudden changes of pressure after weight-bearing or impulse compression is particularly important.
endothelial-derived relaxing factor Binding (liberation) of
2) Confidence 0.05 Published 1990 Journal J Bone Joint Surg Br Section Abstract Doc Link 2211762 Disease Relevance 0.25 Pain Relevance 0.09
Robert Furchgott and John Zawadski recognized the importance of the endothelium in acetylcholine-induced vasorelaxation (in 1980) and Louis Ignarro and Salvador Moncada identified endothelial-derived relaxing factor (EDRF) as NO (in 1987). 9.
endothelial-derived relaxing factor Binding (recognized) of in endothelium
3) Confidence 0.05 Published 2000 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 10779131 Disease Relevance 0.53 Pain Relevance 0.45
Based on these results, we propose that, in vivo, enhanced formation of LPL-9+262 monomer leads to abnormal binding of the mutant lipase to endothelial glycosaminoglycans ultimately resulting in enhanced catabolism of the mutant enzyme and lower enzyme mass in post-heparin plasma.
mutant lipase Binding (binding) of in plasma
4) Confidence 0.02 Published 1996 Journal J. Lipid Res. Section Abstract Doc Link 8728326 Disease Relevance 0 Pain Relevance 0

General Comments

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