INT218732

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Lep, Trh) extracellular space (Lep) plasma membrane (Trh)
nucleus (Trh) intracellular (Lep) cytoplasm (Trh)
Anatomy Link Frequency
PVN 2
Lep (Rattus norvegicus)
Trh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 1 91.24 High High
Eae 2 90.84 High High
Thalamus 1 82.24 Quite High
Spinal cord 1 73.44 Quite High
Neurotransmitter 1 63.60 Quite High
cerebral cortex 3 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
midbrain 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 1 91.24 High High
Cognitive Disorder 2 87.88 High High
Suicidal Behaviour 3 7.36 Low Low
Anorexia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Appetite Loss 2 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Starvation 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRH gene expression in the paraventricular nucleus (PVN) has been shown to be regulated by leptin (Flier and Maratos-Flier 1998; Mantzoros 1999; Nillni et al. 2000).
leptin Regulation (regulated) of Gene_expression (expression) of TRH in PVN
1) Confidence 0.19 Published 2007 Journal Journal of Neurochemistry Section Body Doc Link PMC2156111 Disease Relevance 0.18 Pain Relevance 0.25

General Comments

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