INT219288

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Context Info
Confidence 0.55
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Kcnc1) transmembrane transport (Kcnc1)
Anatomy Link Frequency
cerebellar granule cells 1
myometrium 1
brain 1
Kcnc1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pyramidal cell 16 94.72 High High
potassium channel 4 86.52 High High
Hippocampus 10 84.52 Quite High
Calcium channel 1 77.96 Quite High
Action potential 3 76.56 Quite High
Thalamus 2 74.40 Quite High
agonist 5 41.28 Quite Low
tetrodotoxin 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
repetitive firing 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 2 5.00 Very Low Very Low Very Low
Autism 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low
Dysmenorrhea 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There is also some evidence for potassium currents in myometrium which are voltage gated [15], including evidence for the presence of Kv channels which are assumed to consist of multimers of ?
Localization (presence) of Kv in myometrium
1) Confidence 0.55 Published 2007 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2186335 Disease Relevance 0 Pain Relevance 0.20
Next, we analyzed in more detail the three brain areas where Kv4 protein localization and function have been best characterized.


Localization (localization) of Kv4 in brain
2) Confidence 0.55 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2576564 Disease Relevance 0 Pain Relevance 0.18
A predominant dendritic localization of Kv4.2 proteins has also been observed in other neuronal populations such as in cerebellar granule cells (Rhodes et al., 2004; Sheng et al., 1992; Strassle et al., 2005).
Localization (localization) of Kv4 in cerebellar granule cells
3) Confidence 0.48 Published 2008 Journal Frontiers in Molecular Neuroscience Section Body Doc Link PMC2576564 Disease Relevance 0 Pain Relevance 0.17

General Comments

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