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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.17
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (THRA) nucleoplasm (THRA) nucleus (THRA)
transcription factor binding (THRA)
Anatomy Link Frequency
thyroid 1
neurons 1
ear skin 1
THRA (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 38 99.96 Very High Very High Very High
Acupuncture 26 94.06 High High
Calcium channel 14 82.72 Quite High
analgesia 3 74.92 Quite High
narcan 1 70.16 Quite High
antagonist 1 69.80 Quite High
opiate 1 69.36 Quite High
conotoxin 2 59.76 Quite High
drug abuse 2 59.64 Quite High
withdrawal 2 58.24 Quite High
Disease Link Frequency Relevance Heat
Cancer 14 98.80 Very High Very High Very High
Parathyroid Cancer 1 94.44 High High
Carcinoid 1 87.20 High High
Thyroid Hormone Resistance Syndrome 3 79.84 Quite High
Hypothyroidism 2 78.60 Quite High
Disease 27 59.96 Quite High
Drug Dependence 2 59.64 Quite High
Alcohol Addiction 1 58.24 Quite High
Obesity 4 56.76 Quite High
Functional Bowel Disorder 1 56.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aberrant alternative splicing of thyroid hormone-receptor ?
Positive_regulation (splicing) of thyroid hormone-receptor in thyroid
1) Confidence 0.49 Published 2008 Journal Pituitary Section Body Doc Link PMC2712623 Disease Relevance 0.78 Pain Relevance 0
Auricolotherapy is a treatment diffusing in all over the world, and its patterns follow the principles of Chinese acupuncture, revised and updated, with Chinese maps of the ear; the principles of Paul Nogier and also the principles of reflexology basing on somatotopic maps that do not recognize energetic-based stimulation, while just the evocation of a reflex stimulating precise areas of the ear; moreover are used for stimulation of ear skin many different tools: finger acupressure, laser, electricity, different types of needles, magnetic balls, seeds.
Positive_regulation (stimulation) of ear in ear skin associated with acupuncture
2) Confidence 0.15 Published 2007 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2206232 Disease Relevance 0.40 Pain Relevance 0.63
Figure 2a shows a BLAST representation of EAR element sequence conservation in the human genome.
Positive_regulation (conservation) of EAR
3) Confidence 0.07 Published 2010 Journal Genome Biol Section Body Doc Link PMC2847721 Disease Relevance 0 Pain Relevance 0
-selective agonists, ERB-041, DPN and MF101 increased [Ca2+]i oscillations, amplitudes and synchronizations in neurons from mES cells, whereas ER?
Positive_regulation (increased) of ERB-041 in neurons associated with agonist
4) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2910705 Disease Relevance 0 Pain Relevance 0.33

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