INT220114

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Tnfrsf1a, Esr1) nucleus (Tnfrsf1a, Esr1) plasma membrane (Tnfrsf1a, Esr1)
enzyme binding (Esr1) DNA binding (Esr1) cytoplasm (Esr1)
Tnfrsf1a (Mus musculus)
Esr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 23 80.88 Quite High
cytokine 7 53.04 Quite High
Etanercept 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 5 99.96 Very High Very High Very High
Disease 15 97.20 Very High Very High Very High
Tumor Necrosis Factor Receptor-associated Periodic Syndrome 65 88.16 High High
INFLAMMATION 23 80.88 Quite High
Apoptosis 7 76.96 Quite High
Death 4 68.40 Quite High
Fever 23 50.00 Quite Low
Syndrome 13 5.00 Very Low Very Low Very Low
Necrosis 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In a transfection system mutant, however, TNFR1 did not appear to directly activate ER stress responses, so this seems less likely to be at the crux of the disease mechanism [56].
TNFR1 Positive_regulation (activate) of ER associated with stress and disease
1) Confidence 0.14 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206363 Disease Relevance 1.14 Pain Relevance 0.10

General Comments

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