INT220147

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IGFBP3, IGF1) extracellular region (IGFBP3, IGF1) signal transduction (IGF1)
nucleus (IGFBP3)
IGFBP3 (Homo sapiens)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 77 76.24 Quite High
cytokine 16 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 9 77.32 Quite High
Rheumatoid Arthritis 77 76.24 Quite High
Obesity 14 61.92 Quite High
Disorder Of Lipid Metabolism 4 28.40 Quite Low
INFLAMMATION 11 5.00 Very Low Very Low Very Low
Appetite Loss 8 5.00 Very Low Very Low Very Low
Renal Disease 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IGFBP-3 stabilizes circulating IGF-I, and reductions in IGFBP-3 can contribute to a decrease in IGF-I levels (due to decreased stability of the complex).
IGFBP-3 Positive_regulation (stabilizes) of IGF-I
1) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2206381 Disease Relevance 0.53 Pain Relevance 0.13

General Comments

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