INT220533

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 6.58
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (OFD1) mitosis (OFD1) nucleus (OFD1)
cilium (OFD1) cytoplasm (OFD1)
Anatomy Link Frequency
lung 1
OFD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 83.60 Quite High
Osteoarthritis 3 43.04 Quite Low
Disease Link Frequency Relevance Heat
Cleidocranial Dysplasia 196 100.00 Very High Very High Very High
Adamantinoma 160 100.00 Very High Very High Very High
Metastasis 8 98.40 Very High Very High Very High
Sarcoma 2 98.02 Very High Very High Very High
Chordoma 2 97.56 Very High Very High Very High
Generaliased Trisomy 2 97.52 Very High Very High Very High
Synovial Sarcoma 2 97.36 Very High Very High Very High
Cancer 16 87.00 High High
Pain 3 83.60 Quite High
Arthritis 1 83.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, one case report has noted a case where after the complete excision of the initial lesion, OFD changed into classic AD via an OFD-like AD stage.13,15 Another case reported OFD-like AD with metastasis to the lung.28
Positive_regulation (stage.13,15) of OFD-like in lung associated with adamantinoma, cleidocranial dysplasia and metastasis
1) Confidence 0.27 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628088 Disease Relevance 3.25 Pain Relevance 0
According to a study on the antibodies against a subtype of cytokeratin by Hazelbag et al, cytokeratin (CK) in AD is different from synovial sarcoma, chordoma, or epithelial sarcoma.13 Benassi et al. insisted on a correlation between OFD and AD based on their results that showed positive CK19 and negative CK8 and CK18 staining in both OFD and AD cases.12 In a cytogenetic study, both OFD and AD have trisomies on chromosomes 7, 8, and 12.4,16
Positive_regulation (positive) of OFD associated with sarcoma, adamantinoma, cleidocranial dysplasia, synovial sarcoma, generaliased trisomy and chordoma
2) Confidence 0.27 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628088 Disease Relevance 3.11 Pain Relevance 0
In a 'worst-case scenario', where the OFD is increased to a distance equivalent to that of a subject with an extremely high BMI, the results show the error of magnification to be approximately 8%.
Positive_regulation (increased) of OFD
3) Confidence 0.07 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2211289 Disease Relevance 0.22 Pain Relevance 0.08

General Comments

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