INT221682

Context Info Confidence 0.01 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0.03

enzyme binding (Esr1) DNA binding (Esr1) protein complex (Esr1) cytoplasm (Esr1) lipid binding (Esr1) nucleus (Esr1)

Esr1 (Mus musculus) FRTS (Homo sapiens)

Pain Link Frequency Relevance Heat methotrexate 1 57.16 Inflammation 2 21.24 imagery 5 5.00 palliative 1 5.00

Disease Link Frequency Relevance Heat Triple Negative Breast Cancer 15 85.68 Recurrence 5 62.00 Breast Cancer 16 50.00 Disease 7 48.20 Cancer 13 22.56 Inflammatory Breast Neoplasms 2 21.84 Advanced Or Metastatic Breast Cancer 4 5.00 Death 2 5.00 Residual Neoplasm 2 5.00 Apoptosis 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Among the parameters investigated, low histologic grade, positive ER, positive PR, positive bcl-2 and low level of Ki-67 were associated with prolonged RFS in univariate analysis.

ER Binding (associated) of RFS

1) Confidence 0.01 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2217558 Disease Relevance 0.15 Pain Relevance 0.03

General Comments

This test has worked.