INT221747

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (Gtf3a, Racgap1) nucleus (Gtf3a, Racgap1) cell differentiation (Racgap1)
transport (Racgap1) embryo development (Racgap1) DNA binding (Gtf3a)
Anatomy Link Frequency
plasma 2
Gtf3a (Rattus norvegicus)
Racgap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 3 97.24 Very High Very High Very High
opioid receptor 123 93.96 High High
substance P 5 77.36 Quite High
agonist 30 74.40 Quite High
intrathecal 1 73.32 Quite High
analgesia 9 72.40 Quite High
dorsal root ganglion 12 71.08 Quite High
depression 1 59.92 Quite High
Neuropeptide 2 53.68 Quite High
Pain 15 50.00 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 13 71.08 Quite High
Targeted Disruption 2 68.08 Quite High
Depression 1 59.92 Quite High
Pain 22 50.00 Quite Low
INFLAMMATION 10 17.40 Low Low
Urological Neuroanatomy 10 5.00 Very Low Very Low Very Low
Neuropathic Pain 6 5.00 Very Low Very Low Very Low
Nociception 5 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Epidermal growth factor (EGF) also can promote the rapid translocation of transient receptor potential (TRP) channel C5, although not a GPCR, inducing its insertion into the plasma membrane via activation of the phosphatidylinositide 3-kinase (PI3K) and Rac1, a Rho family GTPase commonly involved in cytoskeletal re-arrangements and initiation of cell morphological changes [36].


factor Positive_regulation (inducing) of Positive_regulation (activation) of GTPase in plasma
1) Confidence 0.00 Published 2007 Journal Mol Pain Section Body Doc Link PMC2219988 Disease Relevance 0.33 Pain Relevance 1.00

General Comments

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