INT222019

Context Info Confidence 0.62 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.14 Pain Relevance 0.03

extracellular region (Wisp2) cell adhesion (Wisp2) plasma membrane (Wisp2) cytoplasm (Wisp2)

Wisp2 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 1 50.88 Inflammation 40 39.28 cytokine 15 8.40 Inflammatory response 3 5.00 metalloproteinase 3 5.00 interstitial cystitis 3 5.00 imagery 3 5.00 ketamine 2 5.00 Mechanotransduction 2 5.00 Inflammatory stimuli 2 5.00

Disease Link Frequency Relevance Heat Cancer 28 87.36 Apoptosis 20 51.68 INFLAMMATION 44 39.28 Overactive Bladder 18 38.52 Dermatological Disease 1 38.16 Disease 4 16.72 Lung Injury 58 5.00 Death 12 5.00 Injury 11 5.00 Bladder Cancer 9 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

(Mm00432802_m1), for Wisp2 (Mm01247817_m1) for Atf4 (Mm00515324_m1) and for Mmp8 (Mm00772335_m1).

Gene_expression (for) of Wisp2

1) Confidence 0.62 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2223071 Disease Relevance 0 Pain Relevance 0

-estradiol metabolism, including: WISP2, ROCK1 (Rho-GTP binding), MYO1B, S100A13, and CD55.

Gene_expression (metabolism) of WISP2

2) Confidence 0.40 Published 2008 Journal BMC Immunol Section Body Doc Link PMC2262873 Disease Relevance 0.14 Pain Relevance 0.03

General Comments

This test has worked.