INT222191

Context Info Confidence 0.07 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.38 Pain Relevance 0.19

cell adhesion (CD9) plasma membrane (CD9)

CD9 (Homo sapiens)

Pain Link Frequency Relevance Heat Multiple sclerosis 65 98.06 cytokine 4 5.84 Inflammation 8 5.00 chemokine 5 5.00 Central nervous system 4 5.00 COX2 1 5.00 Spinal cord 1 5.00 Inflammatory response 1 5.00 Demyelination 1 5.00 rheumatoid arthritis 1 5.00

Disease Link Frequency Relevance Heat Multiple Sclerosis 69 98.06 Apoptosis 6 6.72 Disease 10 5.00 INFLAMMATION 9 5.00 Epstein-barr Virus 8 5.00 Diabetes Mellitus 7 5.00 Infection 3 5.00 Death 2 5.00 Injury 2 5.00 Rheumatoid Arthritis 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

When analyzed in this way, CD83 expression in the MS samples was down regulated by 0.58-fold, SERPINB9 expression was up regulated by 2.47-fold, and CD9 expression was up regulated 3.5-fold relative to the Control samples (Table 6) and these results are in concordance with array data for these genes.

Regulation (regulated) of Gene_expression (expression) of CD9 associated with multiple sclerosis

1) Confidence 0.07 Published 2008 Journal BMC Med Genomics Section Body Doc Link PMC2227948 Disease Relevance 0.38 Pain Relevance 0.19

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