INT222238

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Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cxcl12) plasma membrane (Cxcl12)
Anatomy Link Frequency
neurons 2
Cxcl12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 102 92.48 High High
Demyelination 47 88.24 High High
glial activation 2 86.72 High High
Dorsal horn 2 84.60 Quite High
Spinal cord 7 84.12 Quite High
Peripheral nervous system 1 79.64 Quite High
Hyperalgesia 14 54.44 Quite High
Endogenous opioid 1 51.44 Quite High
Analgesic 1 50.28 Quite High
cytokine 4 42.80 Quite Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 48 88.24 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 85.28 High High
Disease 1 80.60 Quite High
Injury 14 80.16 Quite High
Nociception 14 56.88 Quite High
Hyperalgesia 21 54.44 Quite High
Nervous System Injury 28 43.20 Quite Low
Pain 26 30.36 Quite Low
Neuropathic Pain 17 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 11 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Upregulated CXCR4 expression, however, is primarily restricted to neurons making them a potential target for the release of SDF-1 from glia.
Regulation (target) of Localization (release) of SDF-1 in neurons
1) Confidence 0.22 Published 2007 Journal Mol Pain Section Body Doc Link PMC2228278 Disease Relevance 0.60 Pain Relevance 0.55

General Comments

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