INT222906

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 2.41
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (HLA-DOA) plasma membrane (HLA-DOA)
Anatomy Link Frequency
arm 1
T cells 1
HLA-DOA (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 1 93.68 High High
cytokine 7 68.08 Quite High
cva 6 5.00 Very Low Very Low Very Low
spinal inflammation 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 9 99.92 Very High Very High Very High
Nasopharynx Cancer 103 99.52 Very High Very High Very High
General Immunology 11 98.20 Very High Very High Very High
Fever 33 97.36 Very High Very High Very High
Disease 69 94.96 High High
Sprains And Strains 38 93.00 High High
Epstein-barr Virus 21 82.48 Quite High
Organ Transplantation 15 80.28 Quite High
Carcinoma 13 79.88 Quite High
Infection 32 74.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Donors who are not perfectly matched with the patients, but homozygous for a given HLA locus can also be used (e.g., patient HLA-A2, 3 and donor HLA-A2 only).
Localization (locus) of HLA
1) Confidence 0.25 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0.10 Pain Relevance 0
HLA alloimmunization
Localization (alloimmunization) of HLA
2) Confidence 0.25 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628004 Disease Relevance 0.20 Pain Relevance 0
The HLA System: Genetics, Immunology, Clinical Testing, and Clinical Implications

The human major histocompatibility complex HLA is located on the short arm of chromosome 6.

Localization (located) of HLA in arm associated with general immunology
3) Confidence 0.25 Published 2007 Journal Yonsei Medical Journal Section Title Doc Link PMC2628004 Disease Relevance 0.18 Pain Relevance 0
of endemic populations revealed the association of HLA antigen haplotype with
Localization (haplotype) of HLA
4) Confidence 0.06 Published 2007 Journal Comparative and Functional Genomics Section Body Doc Link PMC2233780 Disease Relevance 1.62 Pain Relevance 0.05
To determine whether the remaining 161 peptides were indeed binders to the relevant HLA class I molecules, they were tested in a biochemical in vitro binding assay.
Localization (relevant) of HLA
5) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939062 Disease Relevance 0.18 Pain Relevance 0.03
In the first round of analysis, the 112 peptides identified as binding with a KD of 500 nM or less for the relevant HLA class I molecule, were tested for their ability to stimulate CD8+ T cells from a study population of 11 WNV-infected patients.
Localization (relevant) of HLA in T cells
6) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2939062 Disease Relevance 0.14 Pain Relevance 0

General Comments

This test has worked.

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