INT224701

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Timp3, TNF) signal transduction (TNF) extracellular space (TNF)
proteinaceous extracellular matrix (Timp3) plasma membrane (TNF) intracellular (TNF)
Timp3 (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 25 100.00 Very High Very High Very High
rheumatoid arthritis 52 94.64 High High
methotrexate 4 11.44 Low Low
Infliximab 1 8.88 Low Low
cytokine 29 5.00 Very Low Very Low Very Low
Inflammation 24 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Severe Combined Immunodeficiency 8 98.24 Very High Very High Very High
Rheumatoid Arthritis 52 94.64 High High
Cancer 7 60.48 Quite High
Metastasis 2 57.76 Quite High
Disease 11 56.92 Quite High
Malignant Neoplastic Disease 1 56.56 Quite High
Apoptosis 28 5.00 Very Low Very Low Very Low
INFLAMMATION 25 5.00 Very Low Very Low Very Low
Adhesions 7 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The same effect was shown for TIMP-3, which in addition to MMPs inhibits TNF-?
TIMP-3 Negative_regulation (inhibits) of TNF associated with metalloproteinase
1) Confidence 0.01 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.65 Pain Relevance 0.34

General Comments

This test has worked.

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