INT225733

Context Info Confidence 0.01 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.06 Pain Relevance 0.04

cytosol (Car2) extracellular space (Car2) lyase activity (Car2) plasma membrane (Entpd8) cytoplasm (Car2)

Car2 (Mus musculus) Entpd8 (Mus musculus)

Pain Link Frequency Relevance Heat adenocard 20 72.96 antagonist 35 5.00 Inflammation 14 5.00 Bile 10 5.00 agonist 8 5.00 Central nervous system 5 5.00 ischemia 5 5.00 Hippocampus 4 5.00 noradrenaline 3 5.00 Kinase C 2 5.00

Disease Link Frequency Relevance Heat General Immunology 1 59.32 INFLAMMATION 12 5.00 Adhesions 6 5.00 Stress 6 5.00 Cirrhosis 5 5.00 Vasculitis 5 5.00 Increased Venous Pressure Under Development 5 5.00 Salivary Gland Disease 3 5.00 Neurological Disease 3 5.00 Hypoxia 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In contrast to NTPDase1 and NTPDase2, murine NTPDase3 and NTPDase8 are preferentially activated by Ca2+ over Mg2+ [52, 58, 59].

Ca2 Positive_regulation (activated) of NTPDase8

1) Confidence 0.01 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254478 Disease Relevance 0.06 Pain Relevance 0.04

General Comments

This test has worked.