INT225776

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.67
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

generation of precursor metabolites and energy (Enpp1) extracellular space (Enpp1) plasma membrane (Enpp1)
Anatomy Link Frequency
chondrocytes 2
Enpp1 (Mus musculus)
Ppi-rs (Mus musculus)
Pain Link Frequency Relevance Heat
Osteoarthritis 15 96.60 Very High Very High Very High
cytokine 3 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Calcification 46 99.32 Very High Very High Very High
Osteoarthritis 15 96.60 Very High Very High Very High
Aging 13 96.20 Very High Very High Very High
Chondrocalcinosis 3 95.84 Very High Very High Very High
Disease 8 88.84 High High
Metabolic Disorder 1 46.08 Quite Low
Osteoporosis 4 27.24 Quite Low
Congenital Anomalies 3 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NPP1 not only directly induces elevated PPi but also matrix calcification by chondrocytes in vitro.
NPP1 Positive_regulation (induces) of Positive_regulation (elevated) of PPi in chondrocytes associated with calcification
1) Confidence 0.08 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2254483 Disease Relevance 1.67 Pain Relevance 0.28

General Comments

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