INT226071

Context Info Confidence 0.09 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.47 Pain Relevance 0.19

peptidase activity (MMP9) extracellular space (MMP9) extracellular region (MMP9) small molecule metabolic process (HSD11B1) oxidoreductase activity (HSD11B1) proteinaceous extracellular matrix (MMP9)

Anatomy Link Frequency heart 1 HSD11B1 (Homo sapiens) MMP9 (Homo sapiens)

Pain Link Frequency Relevance Heat alcohol 18 91.32 Inflammation 6 54.88 metalloproteinase 4 50.00 cytokine 2 5.00 Angina 1 5.00

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 4 100.00 Nicotine Addiction 17 87.16 INFLAMMATION 6 54.88 Coronary Artery Disease 21 29.92 Diabetes Mellitus 6 5.00 Obesity 3 5.00 Acute Coronary Syndrome 3 5.00 Disease 3 5.00 Dyslipidemia / Combined Dyslipidemia 2 5.00 Cardiovascular Disease 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Adjusting for age and sex, level of MMP-9 was significantly associated to the single risk factors waist circumference, SBP, heart rate, low HDL, triglycerides and CRP apart from each of the four behavioral factors tested.

HDL Binding (associated) of MMP-9 in heart associated with disorder of lipid metabolism

1) Confidence 0.09 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2258002 Disease Relevance 0.47 Pain Relevance 0.19

General Comments

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