INT226759

Context Info Confidence 0.01 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.58 Pain Relevance 0.17

endosome (Cxcr4) signal transduction (Cxcr4) extracellular space (Serpinf1) extracellular region (Serpinf1) cytoplasmic membrane-bounded vesicle (Cxcr4) plasma membrane (Cxcr4)

Serpinf1 (Mus musculus) Cxcr4 (Mus musculus)

Pain Link Frequency Relevance Heat Kinase C 4 89.12 imagery 2 5.00 chemokine 1 5.00 Inflammatory response 1 5.00 Opioid 1 5.00

Disease Link Frequency Relevance Heat Acquired Immune Deficiency Syndrome Or Hiv Infection 75 98.96 Apoptosis 4 80.48 Superinfection 4 39.56 Infection 10 12.00 Cancer 3 5.00 INFLAMMATION 1 5.00 Cytomegalovirus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Unlike SDF-induced CXCR4 downregulation, Gag expression had little to no effect on PMA-induced CD4 downregulation (Fig. 5).

SDF Negative_regulation (downregulation) of CXCR4

1) Confidence 0.01 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.58 Pain Relevance 0.17

General Comments

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