INT229466

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Context Info
Confidence 0.76
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.32
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ndel1) transport (Ndel1) nuclear envelope (Ndel1)
chromosome segregation (Ndel1) chromosome (Ndel1) cytoskeleton (Ndel1)
Anatomy Link Frequency
glial cells 1
Schwann cells 1
Ndel1 (Mus musculus)
Pain Link Frequency Relevance Heat
Sciatic nerve 93 96.24 Very High Very High Very High
dorsal root ganglion 57 95.68 Very High Very High Very High
Spinal cord 30 88.64 High High
butorphanol 3 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
Dorsal column 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 66 95.68 Very High Very High Very High
Injury 63 76.80 Quite High
Neuroblastoma 3 64.64 Quite High
Coronary Artery Disease 9 61.84 Quite High
Schizophrenia 3 54.68 Quite High
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Embryonic Lethality 6 5.00 Very Low Very Low Very Low
Nervous System Injury 6 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Consistent with the enriched localization of Ndel1 in neurons, Ndel1 antibodies conjugated to gold particles decorated the IF structures within sciatic nerve axon but were absent from myelin of Schwann cells (Fig. 1D).
Localization (localization) of Ndel1 in Schwann cells associated with sciatic nerve
1) Confidence 0.76 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.38 Pain Relevance 0.43
Axonal localization of the Ndel1/Vimentin complex
Localization (localization) of Ndel1/Vimentin
2) Confidence 0.66 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.46 Pain Relevance 0.20
Importantly, Ndel1 co-localized with Vimentin in a subset of small-diameter axons in these tissues but not with the Vimentin in the basal lamina of glial cells (Fig. 1B, 2nd and 3rd row).
Localization (localized) of Ndel1 in glial cells
3) Confidence 0.66 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2291557 Disease Relevance 0.48 Pain Relevance 0.47

General Comments

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